Research

RESEARCH

The Bayer-Santos Laboratory > Research

DECIPHERING THE MOLECULAR MECHANISM OF (MICRO)BIOLOGICAL CONFLICTS

 

The EBSlab is focused on (micro)biological conflicts and the weapons used by bacteria to target competitors. The group currently uses Salmonella and a specialized contractile nanoweapon called type VI secretion system (T6SS) to understand how enteric pathogens overcome colonization resistance imposed by members of the microbiota and establish an infection. The effectors secreted by the T6SS comprise a pool of proteins with interesting new biochemical activities, providing opportunities for several interdisciplinary projects encompassing microbiology, cell biology, biochemistry, structural biology and bioinformatic.